The cees dekker Diaries
The cees dekker Diaries
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Our team scientific tests bacterial cell division and is aiming to constitute a ‘base up biology’ in synthetic cells that may autonomously divide. Our main desire lies in cell division, chromatin structure, and spatial Command.
, Groningen researchers present the outcomes of their attempts to produce labs far more sustainable and supply methods for other labs.
2007, 1st true-time detection of strand exchange in homologous recombination by RecA; discovery of a minimal persistence length of ends of microtubules; and resolved the system of biosensing with carbon nanotubes
2012, discovery that nucleoid occlusion underlies the precision of bacterial mobile division; and initially at any time examine with the dynamics DNA supercoils and the invention of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
All parameters were being the same for each panel Within this video clip, apart from the Preliminary placement with the 6hb rod (revealed in blue) on the nanopore. Simulations that terminated early because of translocation from the rod with the pore are marked by a grey track record.
Nanopores signify an elegant and flexible Instrument to measure one molecules. We investigate novel detection modes with good-state nanopores as well as various ways to evaluate proteins with nanopores. Jobs encompass the subsequent:
The rotors harness Electrical power from a nanoscale water and ion stream that is certainly generated by a static chemical or electrochemical opportunity gradient while in the nanopore, which can be established by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological situations, suggesting methods to developing Vitality-transducing motors at nanoscale interfaces.
Bulk-surface area coupling identifies the mechanistic relationship concerning Min-protein patterns in vivo and in vitro
[fourteen] In 2005 Dekker turned associated with Netherlands-wide discussions about Clever Style, a motion that he has since Plainly distanced himself from. Dekker advocates that science and faith aren't in opposition but is often harmonized.
Character Physics many thanks the anonymous reviewers for their contribution for the peer critique of the function.
By way of example, we consider the nucleopore elaborate, a gateway between the cell nucleus and ceesdekker also the cytoplasm. This is an extremely intricate procedure and so hard to study in a very cell, so we use biomimetics. We reconstruct holes and afterwards insert specific elements of the nucleopore advanced to study transport by way of it at the single-molecule degree.’
It absolutely was an extremely fascinating time, all through which I obtained a lot of support from Delft College of Engineering, where by I used to be a professor at time, and I begun a number of collaborations with molecular biologists. That helped me understand a whole lot.’